Description

tert-Butyl (3-(Hydroxymethyl)Cyclohexyl)Carbamate is a high-purity, multifunctional chemical intermediate of significant importance in advanced organic synthesis. Its value lies in the simultaneous presence of a protected amine (carbamate) and a hydroxymethyl group, which allows for selective and sequential functionalization. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for constructing complex molecular architectures, particularly in the synthesis of active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly those with cyclohexylamine-based pharmacophores.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where its functional groups enable the creation of targeted bioactive molecules.
• Peptide Mimetics & Conjugation: Serves as a versatile scaffold for creating peptide analogs and for bioconjugation strategies in medicinal chemistry.
• Chiral Auxiliary & Resolving Agent Precursor: The chiral cyclohexane ring makes it a potential precursor for chiral auxiliaries or resolving agents used in asymmetric synthesis.
• Polymer & Material Science: Can be utilized as a monomer or cross-linking agent in the development of specialty polymers with specific functional properties.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	tert-Butyl (3-(Hydroxymethyl)Cyclohexyl)Carbamate
CAS No.	347184-89-8
Molecular Formula	C12H23NO3
Molecular Weight	229.32 g/mol
Synonyms	tert-Butyl N-[3-(hydroxymethyl)cyclohexyl]carbamate; 3-(Hydroxymethyl)cyclohexylcarbamic Acid tert-Butyl Ester; 1,1-Dimethylethyl N-[3-(hydroxymethyl)cyclohexyl]carbamate; (3-Hydroxymethyl-cyclohexyl)-carbamic Acid tert-Butyl Ester; Boc-3-(Hydroxymethyl)cyclohexylamine; Boc-Cyclohexyl(3-hydroxymethyl)amine; tert-Butoxycarbonyl-3-(hydroxymethyl)cyclohexylamine
EINECS	Contact for details

Quality Control

Our tert-Butyl (3-(Hydroxymethyl)Cyclohexyl)Carbamate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and production needs with material suitable for research use and can supply grades aligned with cGMP standards for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.