Description

1-(2-tert-Butoxycarbonylamino-Acetyl)-Piperidine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate featuring a protected amino acid structure. This compound is critical for the synthesis of complex molecules, offering a versatile building block for introducing piperidine and protected amine functionalities. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs), particularly in the areas of protease inhibitors and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially protease inhibitors and other small molecule therapeutics.
• Peptidomimetic Research: Used in the design and construction of peptidomimetics to enhance metabolic stability and bioavailability of peptide-based drugs.
• Chemical Biology & Proteomics: Serves as a valuable scaffold or linker in the development of chemical probes and activity-based protein profiling (ABPP) reagents.
• Custom Synthesis & Contract Manufacturing: Employed by CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client R&D programs.
• Academic Research: Utilized in university and institutional laboratories for methodological development in organic synthesis and medicinal chemistry.

Basic Information

Product Name	1-(2-tert-Butoxycarbonylamino-Acetyl)-Piperidine-4-Carboxylic Acid
CAS No.	345955-48-8
Molecular Formula	C13H22N2O5
Molecular Weight	286.33 g/mol
Synonyms	1-[(2-{[(tert-Butoxy)carbonyl]amino}acetyl)-4-piperidinecarboxylic acid; Boc-Gly-piperidine-4-carboxylic acid; 1-(2-(Boc-amino)acetyl)piperidine-4-carboxylic acid; 4-Carboxy-1-(N-Boc-glycyl)piperidine; N-Boc-glycyl-piperidine-4-carboxylic acid; Piperidine-4-carboxylic acid, 1-[(2-[[(1,1-dimethylethoxy)carbonyl]amino]acetyl]-; 345955-48-8
EINECS	Contact for details

Quality Control

Our production of 1-(2-tert-Butoxycarbonylamino-Acetyl)-Piperidine-4-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. All materials are characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider using a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.