Description

Azetidine-3-Carbonitrile Hydrochloride CAS NO 345954-83-8 is a versatile and highly functionalized heterocyclic building block. This compound is critical for the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by medicinal chemists and process development scientists working in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used as a building block for developing new generation herbicides, fungicides, and insecticides with improved efficacy.
• Chemical Biology & Proteomics: Serves as a valuable scaffold for creating molecular probes, enzyme inhibitors, and activity-based protein profiling (ABPP) reagents.
• Ligand & Catalyst Development: Employed in the design and synthesis of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialized polymers and advanced functional materials.
• Academic & Contract Research: Essential reagent for methodology development and exploratory synthetic chemistry in academic and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	Azetidine-3-Carbonitrile Hydrochloride
CAS No.	345954-83-8
Molecular Formula	C4H7N2•HCl
Molecular Weight	134.58 g/mol
Synonyms	3-Cyanoazetidine Hydrochloride; Azetidine-3-carbonitrile HCl; 3-Azetidinecarbonitrile Hydrochloride; 1-Azacyclobutane-3-carbonitrile Hydrochloride; 3-Cyano-1-azacyclobutane Hydrochloride; Azetidine-3-carbonitrile hydrochloride salt
EINECS	Contact for details

Quality Control

Our Azetidine-3-Carbonitrile Hydrochloride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide full traceability and a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.