Description

4-Morpholineacetonitrile, α-(Hydroxymethylene)- is a versatile and high-value specialty chemical intermediate characterized by its reactive nitrile and hydroxymethylene functional groups. This compound is critical for facilitating complex synthetic transformations, particularly in the construction of heterocyclic frameworks and fine chemical building blocks. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug molecules, particularly those containing morpholine and related heterocycles.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its reactive sites for structural diversification.
• Fine Chemical Production: Serves as a precursor for dyes, pigments, and other performance chemicals requiring specific molecular architectures.
• Academic & Industrial Research: A valuable reagent in methodological development and exploratory chemistry for creating new carbon-carbon and carbon-heteroatom bonds.
• Ligand and Catalyst Development: Potential use in the synthesis of novel chelating agents or organocatalysts due to its donor atom sites.

Basic Information

Product Name	4-Morpholineacetonitrile, α-(Hydroxymethylene)-
CAS No.	345581-21-7
Molecular Formula	C7H10N2O2
Molecular Weight	154.17 g/mol
Synonyms	α-(Hydroxymethylene)-4-morpholineacetonitrile; 2-(Morpholin-4-yl)-2-(hydroxymethylene)acetonitrile; (Hydroxymethylene)(morpholino)acetonitrile; 4-Morpholineacetonitrile, α-(hydroxymethylene)-; Morpholine, 4-[(cyanohydroxymethyl)methyl]-; 2-(Hydroxymethylene)-2-morpholinoacetonitrile
EINECS	Contact for details

Quality Control

Every batch of 4-Morpholineacetonitrile, α-(Hydroxymethylene)- is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.