Description

Tetrahydro-2H-Pyran-4-Carboxamide is a versatile heterocyclic carboxamide building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical compounds and fine chemicals, offering a rigid, oxygen-containing scaffold. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic structure.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of monomers and polymers with specific thermal and mechanical properties.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis projects requiring a defined, high-purity piperidine analogue.

Basic Information

Product Name	Tetrahydro-2H-Pyran-4-Carboxamide
CAS No.	344329-76-6
Molecular Formula	C6H11NO2
Molecular Weight	129.16 g/mol
Synonyms	4-Piperidinecarboxamide, tetrahydro-2H-pyran-4-yl analogue; Oxane-4-carboxamide; Tetrahydropyran-4-carboxamide; 4-Carbamoyltetrahydropyran; THP-4-Carboxamide; 4-Aminocarbonyltetrahydropyran
EINECS	Contact for details

Quality Control

Every batch of Tetrahydro-2H-Pyran-4-Carboxamide is produced under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, supporting cGMP and ISO 9001 standards where applicable. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is available for each lot and provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.