Description

Benzene, 1-(Fluoroethynyl)-4-Methoxy- (9Ci) is a specialized fluorinated aromatic building block of significant interest in advanced organic synthesis. Its unique structure, featuring a fluoroethynyl substituent, makes it a valuable precursor for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel drug candidates, particularly for introducing fluorine atoms and acetylene linkages into bioactive molecules.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluoroethynyl group can enhance biological activity and environmental stability.
• Material Science Research: Acts as a monomer or building block for developing specialty polymers, liquid crystals, and organic electronic materials with specific optoelectronic properties.
• Chemical Biology Probes: Employed in the synthesis of tagged molecules and probes for studying biological mechanisms and diagnostic applications.
• Cross-Coupling Reactions: A valuable substrate in Sonogashira and other palladium-catalyzed cross-coupling reactions to create conjugated systems.

Basic Information

Product Name	Benzene, 1-(Fluoroethynyl)-4-Methoxy- (9Ci)
CAS No.	344256-79-7
Molecular Formula	C9H7FO
Molecular Weight	150.15 g/mol
Synonyms	1-(Fluoroethynyl)-4-methoxybenzene; 4-Methoxyphenyl(fluoro)acetylene; p-Methoxyphenyl fluoroacetylene; (4-Methoxyphenyl)(fluoro)ethyne; 344256-79-7; 1-Fluoroethynyl-4-methoxybenzene
EINECS	Contact for details

Quality Control

Our production of Benzene, 1-(Fluoroethynyl)-4-Methoxy- (9Ci) adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.