Description

2-Cyano-N'-[(Z)-4,4,4-Trifluoro-1-Methyl-3-Oxobutylidene]Acetohydrazide is a specialized organic intermediate featuring a cyanoacetohydrazide core integrated with a trifluoromethyl ketone moiety, offering unique reactivity for advanced synthesis. This compound is valued for its role in constructing complex heterocyclic scaffolds and as a key building block in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for its ability to introduce functional complexity into target molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting metabolic and central nervous system disorders.
• Agrochemical Synthesis: Used in the research and development of new herbicides and fungicides, leveraging the trifluoromethyl group for enhanced bioactivity and stability.
• Heterocyclic Chemistry: Serves as a versatile scaffold for constructing pyrazole, pyrimidine, and other nitrogen-containing heterocycles important in medicinal chemistry.
• Chemical Research & Development: Employed in academic and industrial labs for method development and exploring new reaction pathways in organic synthesis.
• Material Science Precursor: Investigated for the synthesis of specialized polymers and ligands with unique electronic or binding properties.

Basic Information

Product Name	2-Cyano-N'-[(Z)-4,4,4-Trifluoro-1-Methyl-3-Oxobutylidene]Acetohydrazide
CAS No.	343955-25-9
Molecular Formula	C8H8F3N3O2
Molecular Weight	235.16 g/mol
Synonyms	2-Cyano-N'-[(1Z)-4,4,4-trifluoro-1-methyl-3-oxobutylidene]acetohydrazide; (Z)-2-Cyano-N'-(4,4,4-trifluoro-1-methyl-3-oxobutylidene)acetohydrazide; 2-Cyano-N'-(4,4,4-trifluoro-1-methyl-3-oxobutylidene)acetohydrazide; Acetohydrazide, 2-cyano-N'-[(1Z)-4,4,4-trifluoro-1-methyl-3-oxobutylidene]-; 343955-25-9; TFMO-CAH; Trifluoromethyl Ketone Cyanoacetohydrazide
EINECS	Contact for details

Quality Control

Our 2-Cyano-N'-[(Z)-4,4,4-Trifluoro-1-Methyl-3-Oxobutylidene]Acetohydrazide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP guidelines for pharmaceutical intermediates and other relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.