Description

Pentanoic Acid, 3-Ethyl-3-Fluoro-2-Oxo-, Methyl Ester is a specialized fluorinated keto-ester building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, combining a fluorine atom and a reactive keto-ester group, which makes it a versatile precursor for constructing complex molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as medicinal chemistry and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key fluorinated synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in lead optimization and prodrug design.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides where the introduction of fluorine can enhance biological activity and environmental stability.
• Advanced Material Precursor: Serves as a building block for specialty polymers, liquid crystals, or organic electronic materials requiring specific fluorinated components.
• Chemical Research & Development: Employed in academic and industrial labs for methodology development, exploring new fluorination reactions, and synthesizing complex natural product analogs.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up campaigns under cGMP or ISO standards for client-specific molecules.

Basic Information

Product Name	Pentanoic Acid, 3-Ethyl-3-Fluoro-2-Oxo-, Methyl Ester
CAS No.	343865-83-8
Molecular Formula	C8H13FO3
Molecular Weight	176.18 g/mol
Synonyms	Methyl 3-Ethyl-3-fluoro-2-oxopentanoate; 3-Ethyl-3-fluoro-2-oxopentanoic acid methyl ester; 2-Oxopentanoic acid, 3-ethyl-3-fluoro-, methyl ester; Fluorinated keto-ester building block; 3-Fluoro-3-ethyl-2-oxopentanoate methyl ester
EINECS	Contact for details

Quality Control

Our Pentanoic Acid, 3-Ethyl-3-Fluoro-2-Oxo-, Methyl Ester is produced and handled under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support development and commercial projects with material suitable for research use and can supply under more stringent quality agreements for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its highly volatile nature, keep containers tightly sealed when not in use and away from heat sources and open flames. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong bases and fluorides.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.