Description

Cyclopropanecarbonitrile, 1-[(Tetrahydro-2H-Pyran-2-Yl)Oxy]- (9Ci) is a high-purity, protected nitrile building block essential for advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought by medicinal chemists and process development scientists for the synthesis of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new therapeutic agents.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Process Chemistry: Serves as a versatile building block in the scalable synthesis of complex target molecules.
• Agrochemical Research: Employed in the synthesis of novel compounds for crop protection and agricultural science.
• Academic Research: A valuable reagent for methodological development and the synthesis of novel heterocyclic compounds in university and institutional labs.
• Custom Synthesis: Used by contract research and manufacturing organizations (CROs/CMOs) for client-specific projects requiring protected functional groups.

Basic Information

Product Name	Cyclopropanecarbonitrile, 1-[(Tetrahydro-2H-Pyran-2-Yl)Oxy]- (9Ci)
CAS No.	343787-91-7
Molecular Formula	C9H13NO2
Molecular Weight	167.21 g/mol
Synonyms	1-[(Tetrahydro-2H-pyran-2-yl)oxy]cyclopropanecarbonitrile; 1-(Tetrahydro-2H-pyran-2-yloxy)cyclopropanecarbonitrile; 1-(Oxiran-2-ylmethoxy)cyclopropanecarbonitrile (related); Cyclopropanecarbonitrile, 1-[(tetrahydro-2H-pyran-2-yl)oxy]-; THP-protected cyclopropanecarbonitrile; 1-(THP-Oxy)cyclopropanecarbonitrile; 1-(Tetrahydropyran-2-yloxy)cyclopropanecarbonitrile; 343787-91-7
EINECS	Contact for details

Quality Control

Our Cyclopropanecarbonitrile, 1-[(Tetrahydro-2H-Pyran-2-Yl)Oxy]- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.