Description

2-[1-Amino-2-(4-Fluorophenoxy)Ethylidene]Malononitrile is a high-purity, specialized organic intermediate featuring a unique molecular scaffold that combines a fluorinated aromatic ether with a reactive malononitrile moiety. This compound is critical for advanced chemical synthesis, enabling the construction of complex heterocyclic systems and functional materials. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Research: Used in the development of next-generation herbicides and fungicides, leveraging the fluorophenoxy group for enhanced biological activity and environmental stability.
• Organic Electronics: Acts as a precursor for electron-deficient units in the synthesis of n-type semiconductors and non-fullerene acceptors for organic photovoltaics (OPVs).
• Dye & Pigment Synthesis: Employed in the creation of advanced functional dyes, including near-infrared (NIR) absorbers and fluorescent markers for bio-imaging.
• Ligand & Catalyst Development: Utilized to construct novel chelating ligands for transition metal catalysis in asymmetric synthesis.
• Polymer Modification: Incorporated as a functional monomer to introduce specific photoactive or electronic properties into specialty polymer backbones.

Basic Information

Product Name	2-[1-Amino-2-(4-Fluorophenoxy)Ethylidene]Malononitrile
CAS No.	343375-38-2
Molecular Formula	C₁₁H₈FN₃O
Molecular Weight	217.20 g/mol
Synonyms	2-[1-Amino-2-(4-fluorophenoxy)ethylidene]propanedinitrile; (Z)-2-(1-Amino-2-(4-fluorophenoxy)ethylidene)malononitrile; 2-(1-Amino-2-(4-fluorophenoxy)ethylidene)malononitrile; 4-Fluorophenoxyacetonitrile derivative; Propanedinitrile, 2-[1-amino-2-(4-fluorophenoxy)ethylidene]-; Amino(4-fluorophenoxy)ethylidenemalononitrile
EINECS	Contact for details

Quality Control

Every batch of 2-[1-Amino-2-(4-Fluorophenoxy)Ethylidene]Malononitrile is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency, meeting the stringent requirements of research and process development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.