Description

(S)-3-Methyl-5-(2-Pyrrolidinyl)-1,2,4-Oxadiazole CAS NO 343246-61-7 is a high-purity, chiral heterocyclic compound featuring a 1,2,4-oxadiazole core fused with a pyrrolidine ring. This specific stereochemistry makes it a valuable and versatile building block in modern pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists working in medicinal chemistry. The compound's structure is ideal for creating novel drug candidates targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder research.
• Medicinal Chemistry Research: Serves as a privileged scaffold for constructing compound libraries in high-throughput screening (HTS) for novel drug discovery.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce stereoselectivity.
• Chemical Biology Probe Development: Used to create molecular probes for studying enzyme function and biological pathways due to its heterocyclic structure.
• Agrochemical Research: Potential intermediate in the development of new, chiral agrochemicals with enhanced activity and selectivity.

Basic Information

Product Name	(S)-3-Methyl-5-(2-Pyrrolidinyl)-1,2,4-Oxadiazole
CAS No.	343246-61-7
Molecular Formula	C7H11N3O
Molecular Weight	153.18 g/mol
Synonyms	(S)-3-Methyl-5-(pyrrolidin-2-yl)-1,2,4-oxadiazole; (2S)-2-(3-Methyl-1,2,4-oxadiazol-5-yl)pyrrolidine; (S)-5-(2-Pyrrolidinyl)-3-methyl-1,2,4-oxadiazole; 3-Methyl-5-[(2S)-2-pyrrolidinyl]-1,2,4-oxadiazole; (S)-3-Methyl-5-(2-pyrrolidinyl)-1,2,4-oxadiazole; L-3-Methyl-5-(2-pyrrolidinyl)-1,2,4-oxadiazole; (S)-Oxadiazole-pyrrolidine derivative
EINECS	Contact for details

Quality Control

Every batch of (S)-3-Methyl-5-(2-Pyrrolidinyl)-1,2,4-Oxadiazole is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including chiral HPLC, to ensure high enantiomeric purity and chemical identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.