Description

Hepcidin-22 (Human) CAS NO 342790-22-1 is a synthetic peptide hormone that plays a central role in the regulation of systemic iron homeostasis. This bioactive compound is critical for researchers and developers in the life sciences sector, as it directly inhibits iron absorption and release. It is primarily utilized in advanced biochemical research, pharmaceutical development for anemia and iron-overload disorders, and as a key reference standard in diagnostic assay development.

Application

• Biomedical Research: Fundamental studies on iron metabolism, hormone function, and related signaling pathways.
• Pharmaceutical R&D: Target molecule for developing novel therapeutics for conditions like hemochromatosis, anemia of chronic disease, and β-thalassemia.
• Diagnostic Development: Essential reference standard and calibrator for ELISA kits and other immunoassays measuring hepcidin levels.
• Cell Culture & In Vitro Studies: Used to modulate iron levels and study cellular responses in various experimental models.
• Peptide Chemistry & Conjugation: Serves as a starting material or model compound for structural-activity relationship (SAR) studies and bioconjugation.

Basic Information

Product Name	Hepcidin-22 (Human)
CAS No.	342790-22-1
Molecular Formula	C112H179N41O32S9
Molecular Weight	2789.4 g/mol
Synonyms	Hepcidin-25 (Human) fragment 1-22; Liver-expressed antimicrobial peptide 1 (1-22); LEAP-1 (1-22); HAMP (1-22); Hepc22; Iron regulatory hormone peptide; Hepcidin antimicrobial peptide fragment
EINECS	Contact for details

Quality Control

Our Hepcidin-22 (Human) is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including reversed-phase HPLC for purity and mass spectrometry for identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (Mass Spec)	Consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.