Description

N,n-Bis((S)-1-Phenylethyl) Phthalamic Acid is a high-purity chiral intermediate of significant importance in asymmetric synthesis and pharmaceutical development. Its value lies in its role as a versatile building block for constructing complex molecules with defined stereochemistry, crucial for creating active pharmaceutical ingredients (APIs) and advanced materials. This compound is primarily needed by research institutions, fine chemical manufacturers, and pharmaceutical companies engaged in the development of novel therapeutics, chiral catalysts, and specialty chemicals.

Application

• Chiral Auxiliary in Asymmetric Synthesis: Used to induce stereoselectivity in the formation of carbon-carbon and carbon-heteroatom bonds.
• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of enantiomerically pure drug candidates and active pharmaceutical ingredients (APIs).
• Ligand Precursor for Catalysts: Can be utilized in the development of chiral ligands for transition metal catalysis.
• Research & Development: Employed in academic and industrial R&D for exploring new synthetic methodologies and chiral compound libraries.
• Fine Chemical Production: Acts as a building block for high-value specialty chemicals requiring specific stereochemical configurations.
• Reference Standard: Used as a high-purity analytical standard for method development and quality control in chiral analysis.

Basic Information

Product Name	N,n-Bis((S)-1-Phenylethyl) Phthalamic Acid
CAS No.	340168-99-2
Molecular Formula	C24H23NO3
Molecular Weight	373.45 g/mol
Synonyms	N,N-Bis[(1S)-1-Phenylethyl]phthalamic Acid; (S,S)-N,N-Bis(1-Phenylethyl)phthalamic Acid; Phthalamic Acid, N,N-bis[(1S)-1-phenylethyl]-; N,N-Bis((S)-α-Methylbenzyl)phthalamic Acid; (S,S)-N,N-Di(1-phenylethyl)phthalamic Acid; Chiral Phthalamic Acid Derivative; BINOL-Related Chiral Auxiliary Precursor
EINECS	Contact for details

Quality Control

Our N,n-Bis((S)-1-Phenylethyl) Phthalamic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and synthesis applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.