Description

Ethylbromofluoroacetate CAS NO 339586-00-4 is a specialized fluorinated building block of significant interest in advanced organic synthesis. This compound is valued for its unique reactivity profile, enabling the efficient introduction of both bromo and fluoro functional groups into target molecules. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of fluorinated drug candidates, particularly in medicinal chemistry programs targeting protease inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Used to construct fluorinated analogs of pesticides and herbicides, leveraging the fluorine atom to enhance metabolic stability and bioavailability.
• Fluorine Chemistry Research: Serves as a versatile electrophile for introducing the -CHFCOOEt moiety in methodological studies and the development of new fluorination reactions.
• Material Science Precursor: Employed in the synthesis of specialized monomers or ligands for advanced polymers and functional materials.
• PET (Positron Emission Tomography) Tracer Development: Potential use as a precursor for synthesizing fluorine-18 labeled compounds for diagnostic imaging, given its fluoroacetate backbone.

Basic Information

Product Name	Ethylbromofluoroacetate
CAS No.	339586-00-4
Molecular Formula	C4H6BrFO2
Molecular Weight	185.00 g/mol
Synonyms	Ethyl bromofluoroacetate; Bromofluoroacetic acid ethyl ester; Ethyl 2-bromo-2-fluoroacetate; 2-Bromo-2-fluoroacetic acid ethyl ester; Acetic acid, 2-bromo-2-fluoro-, ethyl ester; Ethyl α-bromo-α-fluoroacetate; Ethyl bromo(fluoro)acetate; Bromofluoroethyl acetate
EINECS	Contact for details

Quality Control

Our Ethylbromofluoroacetate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. We provide detailed Certificates of Analysis (COA) with every shipment, documenting key parameters such as assay and impurity profiles. Our quality system is designed to meet the stringent requirements of research and fine chemical synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, containers should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to maintain product integrity. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.