Description

[(9H-Fluoren-9-Ylmethoxycarbonylamino)]-Naphthalen-1-Yl-Acetic Acid is a specialized, high-purity chemical building block primarily used in advanced organic synthesis. This compound matters for its role as a key intermediate in the production of complex molecules, particularly in pharmaceutical research and development. It is essential for chemists and manufacturers in the life sciences sector who require reliable, high-quality intermediates for peptide synthesis, drug discovery, and the development of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis, particularly where naphthalene-based amino acid derivatives are required.
• Protecting Group Chemistry: Serves as a reagent in Fmoc (9-fluorenylmethoxycarbonyl) protection strategies for amines during complex organic syntheses.
• Bioconjugation: Employed in the development of antibody-drug conjugates (ADCs) and other targeted therapeutic agents.
• Chemical Biology Research: Utilized in the synthesis of probes and labeled compounds for studying biological mechanisms and interactions.
• Material Science: Potential intermediate for the synthesis of organic semiconductors, dyes, and advanced polymeric materials.

Basic Information

Item	Details
Product Name	[(9H-Fluoren-9-Ylmethoxycarbonylamino)]-Naphthalen-1-Yl-Acetic Acid
CAS No.	339208-92-3
Molecular Formula	C27H21NO4
Molecular Weight	423.46 g/mol
Synonyms	Fmoc-1-Nal-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-1-naphthylalanine; Fmoc-1-Naphthylalanine; 1-Naphthylalanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-; N-α-Fmoc-1-naphthylalanine; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(naphthalen-1-yl)propanoic acid (related isomer); N-Fmoc-1-naphthylalanine; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our [(9H-Fluoren-9-Ylmethoxycarbonylamino)]-Naphthalen-1-Yl-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available for every lot upon request, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.