Description

(4-Chloro-Phenyl)-[(9H-Fluoren-9-Ylmethoxycarbonylamino)]-Acetic Acid is a specialized Fmoc-protected amino acid derivative, a critical building block in modern solid-phase peptide synthesis (SPPS). Its value lies in enabling the precise and efficient construction of complex peptide sequences, particularly those requiring the incorporation of a 4-chlorophenylglycine moiety. This high-purity intermediate is essential for research and development laboratories in the pharmaceutical, biotechnology, and life sciences sectors focused on novel peptide therapeutics, diagnostics, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid for the automated, stepwise assembly of custom peptide chains.
• Pharmaceutical R&D: Used in the discovery and development of peptide-based drugs, hormones, and enzyme inhibitors.
• Bioconjugation: Serves as a linker or spacer molecule for attaching peptides to other biomolecules, surfaces, or reporter groups.
• Combinatorial Chemistry: A valuable reagent in libraries for high-throughput screening of bioactive peptide compounds.
• Academic Research: Fundamental tool for studying protein-protein interactions, signal transduction, and structure-activity relationships (SAR).
• Production of Non-Natural Amino Acids: Intermediate for the synthesis of more complex, tailor-made amino acid analogs.

Basic Information

Product Name	(4-Chloro-Phenyl)-[(9H-Fluoren-9-Ylmethoxycarbonylamino)]-Acetic Acid
CAS No.	339208-91-2
Molecular Formula	C23H18ClNO4
Molecular Weight	407.85 g/mol
Synonyms	Fmoc-4-chloro-DL-phenylglycine; Fmoc-(4-Cl)-Phg-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-4-chloro-DL-phenylglycine; (4-Chlorophenyl)((9H-fluoren-9-ylmethoxy)carbonylamino)acetic acid; N-Fmoc-4-chlorophenylglycine; Fmoc-4-Cl-Phg-OH; 2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(4-chlorophenyl)acetic acid; N-α-Fmoc-4-chloro-DL-phenylglycine
EINECS	Contact for details

Quality Control

Our (4-Chloro-Phenyl)-[(9H-Fluoren-9-Ylmethoxycarbonylamino)]-Acetic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive synthetic applications. We provide comprehensive analytical data, including HPLC chromatograms, to verify identity and purity. Certificates of Analysis (COA) detailing specific lot results are available upon request and accompany every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed in a desiccated environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.