Description

(3-Chloro-Phenyl)-[(9H-Fluoren-9-Ylmethoxycarbonylamino)]-Acetic Acid is a specialized Fmoc-protected amino acid derivative, a critical building block in modern solid-phase peptide synthesis (SPPS). Its value lies in enabling the precise and efficient construction of complex peptides, particularly those requiring the incorporation of modified phenylalanine residues. This high-purity intermediate is essential for research and development laboratories in the pharmaceutical and biotechnology sectors focused on novel therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid building block for the automated synthesis of custom peptide sequences.
• Pharmaceutical R&D: Used in the research and development of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Bioconjugation: Serves as a precursor for creating peptide-protein or peptide-small molecule conjugates for targeted therapies.
• Chemical Biology Probes: Enables the synthesis of labeled or modified peptides used as probes to study biological processes and protein interactions.
• Combinatorial Chemistry: A valuable component in libraries for high-throughput screening to discover new bioactive compounds.
• Academic Research: Supports fundamental research in biochemistry, medicinal chemistry, and molecular biology.

Basic Information

Product Name	(3-Chloro-Phenyl)-[(9H-Fluoren-9-Ylmethoxycarbonylamino)]-Acetic Acid
CAS No.	339208-90-1
Molecular Formula	C23H18ClNO4
Molecular Weight	407.85 g/mol
Synonyms	Fmoc-3-chloro-L-phenylglycine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-chloro-L-phenylglycine; Fmoc-3-Cl-Phg-OH; (3-Chlorophenyl)(((9H-fluoren-9-yl)methoxy)carbonylamino)acetic acid; N-Fmoc-3-chlorophenylglycine; 2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(3-chlorophenyl)acetic acid; Fmoc-3-chloro-DL-phenylglycine (racemic mixture)
EINECS	Contact for details

Quality Control

Our (3-Chloro-Phenyl)-[(9H-Fluoren-9-Ylmethoxycarbonylamino)]-Acetic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemical and pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Purity (Chiral HPLC)	≥ 99.0% ee (L-isomer)
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.