Description

2-[(4-Fluorophenyl)Sulfonyl]-1-(4-Hydroxy-3,5-Dimethylphenyl)-1-Ethanone is a specialized organic intermediate featuring a sulfonyl linker and a hydroxy-substituted aromatic ketone, making it a valuable synthon for constructing complex molecular architectures. Its precise structure offers significant utility in advanced pharmaceutical research and fine chemical synthesis, where high-purity building blocks are critical. This compound is primarily targeted at R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders or inflammatory pathways.
• Agrochemical Research: Used in the development of new generation herbicides or fungicides, leveraging its sulfonyl and fluorinated aryl components.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers with specific thermal or optical properties.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a scaffold for designing enzyme inhibitors.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing high-value, low-volume specialty chemicals.

Basic Information

Product Name	2-[(4-Fluorophenyl)Sulfonyl]-1-(4-Hydroxy-3,5-Dimethylphenyl)-1-Ethanone
CAS No.	339100-34-4
Molecular Formula	C₁₆H₁₅FO₄S
Molecular Weight	322.35 g/mol
Synonyms	1-(4-Hydroxy-3,5-dimethylphenyl)-2-[(4-fluorophenyl)sulfonyl]ethanone; 2-(4-Fluorobenzenesulfonyl)-1-(4-hydroxy-3,5-dimethylphenyl)ethan-1-one; 4-Fluoro-α-oxo-2,4,6-trimethylbenzenepropanesulfonic acid β-sultone derivative (obsolete); 339100-34-4; p-Fluorophenyl 4-hydroxy-3,5-dimethylphenacyl sulfone
EINECS	Contact for details

Quality Control

Our 2-[(4-Fluorophenyl)Sulfonyl]-1-(4-Hydroxy-3,5-Dimethylphenyl)-1-Ethanone is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production standards. Custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.