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n-(2,4-Dichloro-5-Isopropoxyphenyl)-3-(2-Fluoro-4-Nitrophenoxy)-2-Thiophenecarboxamide CAS NO 339015-57-5


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CAS No.:339015-57-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

n-(2,4-Dichloro-5-Isopropoxyphenyl)-3-(2-Fluoro-4-Nitrophenoxy)-2-Thiophenecarboxamide is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound matters for its role as a critical building block in the development of novel therapeutic agents, offering researchers and manufacturers a reliable and well-characterized starting material. It is primarily needed by pharmaceutical R&D laboratories and fine chemical producers engaged in the development of new drug candidates, particularly in areas requiring sophisticated heterocyclic chemistry.

Application

  • Key intermediate in the research and synthesis of novel pharmaceutical compounds.
  • Building block for the development of potential kinase inhibitors and other targeted therapies.
  • Used in medicinal chemistry for structure-activity relationship (SAR) studies.
  • Precursor in the custom synthesis of complex molecules for preclinical and clinical trials.
  • Critical material for process chemistry development and scale-up in API manufacturing.
  • Reference standard for analytical method development and quality control in pharmaceutical production.

Basic Information

Product Name n-(2,4-Dichloro-5-Isopropoxyphenyl)-3-(2-Fluoro-4-Nitrophenoxy)-2-Thiophenecarboxamide
CAS No. 339015-57-5
Molecular Formula C20H15Cl2FN2O5S
Molecular Weight 485.31 g/mol
Synonyms 2-Thiophenecarboxamide, N-(2,4-dichloro-5-isopropoxyphenyl)-3-(2-fluoro-4-nitrophenoxy)-; 339015-57-5; N-(2,4-Dichloro-5-isopropoxyphenyl)-3-(2-fluoro-4-nitrophenoxy)thiophene-2-carboxamide; 3-(2-Fluoro-4-nitrophenoxy)-N-(2,4-dichloro-5-isopropoxyphenyl)-2-thiophenecarboxamide; Thiophene-2-carboxamide derivative; Pharmaceutical Intermediate 339015-57-5
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Quality Control

Our n-(2,4-Dichloro-5-Isopropoxyphenyl)-3-(2-Fluoro-4-Nitrophenoxy)-2-Thiophenecarboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under inert atmosphere when not in use to prevent degradation and moisture uptake.

Specification

Item Specification
Appearance Off-white to light yellow crystalline powder
Identification (HPLC) Conforms to reference standard
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Related Substances (HPLC) Total impurities ≤ 2.0%
Single Maximum Unknown Impurity ≤ 0.5%
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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