Description

2-Phenyl-4-(Trifluoromethyl)-1,3-thiazole-5-carboxylic acid is a high-value, multifunctional heterocyclic building block characterized by its phenyl-substituted thiazole core and trifluoromethyl group. This compound is essential for advanced organic synthesis, where its unique structure imparts desirable physicochemical properties to target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for anti-inflammatory, antiviral, or central nervous system (CNS) targeted therapies.
• Agrochemical Synthesis: Used in the design and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for functional organic materials, such as liquid crystals, organic semiconductors, or metal-organic frameworks (MOFs).
• Chemical Biology Probe Development: Employed as a scaffold for creating molecular probes to study enzyme function or cellular pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical manufacturers offering bespoke synthesis services to clients in life sciences.

Basic Information

Product Name	2-Phenyl-4-(Trifluoromethyl)-1,3-thiazole-5-carboxylic Acid
CAS No.	338982-16-4
Molecular Formula	C11H6F3NO2S
Molecular Weight	273.23 g/mol
Synonyms	5-Thiazolecarboxylic acid, 2-phenyl-4-(trifluoromethyl)-; 2-Phenyl-4-(trifluoromethyl)thiazole-5-carboxylic acid; 4-(Trifluoromethyl)-2-phenyl-1,3-thiazole-5-carboxylic acid; 2-Phenyl-4-trifluoromethylthiazole-5-carboxylic acid; 338982-16-4; 2-Phenyl-4-(trifluoromethyl)-5-thiazolecarboxylic acid
EINECS	Contact for details

Quality Control

Our production of 2-Phenyl-4-(Trifluoromethyl)-1,3-thiazole-5-carboxylic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP and ISO 9001 compliant manufacturing for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.