Description

2-(4-Chlorophenyl)-2-(4-[Hydroxy(Phenyl)Methyl]Phenyl)Acetonitrile is a high-purity, synthetic organic compound featuring a benzhydrol and nitrile functional group, making it a versatile chiral intermediate for advanced chemical synthesis. Its molecular structure is critical for constructing complex pharmacologically active molecules, offering precise stereochemical control. This intermediate is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its chlorophenyl moiety.
• Chemical Research & Development: Serves as a critical substrate in asymmetric synthesis and methodology development for creating complex organic molecules.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals requiring high stereochemical purity and specific aromatic substitution patterns.

Basic Information

Product Name	2-(4-Chlorophenyl)-2-(4-[Hydroxy(Phenyl)Methyl]Phenyl)Acetonitrile
CAS No.	338965-27-8
Molecular Formula	C21H16ClNO
Molecular Weight	333.81 g/mol
Synonyms	α-(4-Chlorophenyl)-α-[4-(hydroxydiphenylmethyl)phenyl]acetonitrile; 2-(4-Chlorophenyl)-2-[4-(hydroxydiphenylmethyl)phenyl]acetonitrile; 4'-[Hydroxy(diphenyl)methyl]-4-chlorobenzhydrylonitrile; (4-Chlorophenyl)[4-(hydroxydiphenylmethyl)phenyl]acetonitrile; Benzhydrol derivative intermediate; CAS 338965-27-8
EINECS	Contact for details

Quality Control

Our 2-(4-Chlorophenyl)-2-(4-[Hydroxy(Phenyl)Methyl]Phenyl)Acetonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical intermediate applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.