Description

1,3-Bis[(Di-tert-Butylphosphino)Oxy]Benzene is a specialized organophosphorus ligand with the CAS number 338800-20-7. This compound is valued for its robust electron-donating and steric properties, which are critical for modulating the activity and selectivity of transition metal catalysts. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries for developing and scaling up advanced catalytic processes, particularly cross-coupling and hydrogenation reactions.

Application

• Homogeneous Catalysis: As a key ligand for palladium, nickel, and other transition metals in cross-coupling reactions (e.g., Suzuki, Heck, Buchwald-Hartwig).
• Pharmaceutical Intermediates: Enabling the synthesis of complex, high-value drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in catalytic steps for manufacturing advanced pesticides and herbicides.
• Material Science Research: Facilitating the development of novel polymers and functional materials via metal-mediated polymerization.
• Asymmetric Synthesis: Potential application in creating chiral ligands for enantioselective catalytic transformations.
• Academic & Industrial R&D: A valuable tool for exploring new catalytic methodologies and reaction pathways in laboratory settings.

Basic Information

Product Name	1,3-Bis[(Di-tert-Butylphosphino)Oxy]Benzene
CAS No.	338800-20-7
Molecular Formula	C22H40O2P2
Molecular Weight	398.50 g/mol
Synonyms	1,3-Bis(di-tert-butylphosphinoxy)benzene; 1,3-Phenylene Bis(di-tert-butylphosphinite); Di-tert-butyl[3-(di-tert-butylphosphinoxy)phenoxy]phosphine; 338800-20-7; B3BDPOB; (3-(Di-tert-butylphosphanyloxy)phenyl) di-tert-butylphosphinite
EINECS	Contact for details

Quality Control

Our production of 1,3-Bis[(Di-tert-Butylphosphino)Oxy]Benzene adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity, which is essential for catalytic performance. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store under an inert atmosphere (argon or nitrogen) at 2-8°C. This product is easily oxidized (store under inert atmosphere). Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
31P NMR Purity	Conforms
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.