Description

1-(4-Fluorophenyl)-2-([5-(Hydroxymethyl)-1-Methyl-1H-Imidazol-2-Yl]Sulfanyl)-1-Ethanone is a high-value, structurally complex organic compound featuring a fluorophenyl ketone linked to a functionalized imidazole ring via a thioether bridge. This unique molecular architecture makes it a critical advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily sought after by R&D and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or infectious diseases.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs) in drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of novel pesticides or herbicides, leveraging the bioactivity of the fluorinated aromatic and heterocyclic components.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes to study enzyme function or biological pathways, thanks to its modifiable hydroxymethyl and ketone groups.
• Fine Chemical Manufacturing: Acts as a specialized building block for the custom synthesis of complex, high-value molecules for various industrial and research applications.

Basic Information

Product Name	1-(4-Fluorophenyl)-2-([5-(Hydroxymethyl)-1-Methyl-1H-Imidazol-2-Yl]Sulfanyl)-1-Ethanone
CAS No.	338422-62-1
Molecular Formula	C13H13FN2O2S
Molecular Weight	280.32 g/mol
Synonyms	1-(4-Fluorophenyl)-2-[(5-hydroxymethyl-1-methyl-1H-imidazol-2-yl)thio]ethanone; 2-[(5-Hydroxymethyl-1-methyl-1H-imidazol-2-yl)thio]-1-(4-fluorophenyl)ethan-1-one; 1-(4-Fluorophenyl)-2-[(1-methyl-5-(hydroxymethyl)-1H-imidazol-2-yl)thio]ethanone; CAS 338422-62-1; FPHMIE; 4-Fluoro-α-[(1-methyl-5-(hydroxymethyl)imidazol-2-yl)thio]acetophenone
EINECS	Contact for details

Quality Control

Our production of 1-(4-Fluorophenyl)-2-([5-(Hydroxymethyl)-1-Methyl-1H-Imidazol-2-Yl]Sulfanyl)-1-Ethanone adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our facilities operate under cGMP principles to guarantee the traceability and reliability required for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect the product from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.