Description

5-Chloro-n-[(Dimethylamino)Methylene]-3-Phenyl-1H-Indole-2-Carboxamide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the research and development of novel therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers requiring a reliable supply of specialized building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel indole-based drug candidates.
• Oncology Research: Used in the development of small molecule inhibitors targeting specific cancer pathways.
• CNS Drug Discovery: Employed as a precursor for compounds with potential activity in neurological disorders.
• Chemical Biology: Utilized as a probe or tool compound in biochemical and pharmacological studies.
• Process Chemistry: Acts as a critical intermediate in the scale-up and optimization of active pharmaceutical ingredient (API) manufacturing routes.
• Academic Research: Used in university and institutional labs for synthetic methodology development and medicinal chemistry projects.

Basic Information

Item	Detail
Product Name	5-Chloro-n-[(Dimethylamino)Methylene]-3-Phenyl-1H-Indole-2-Carboxamide
CAS No.	338401-01-7
Molecular Formula	C19H16ClN3O
Molecular Weight	337.80 g/mol
Synonyms	5-Chloro-3-phenyl-1H-indole-2-carboxamide, N-(dimethylamino)methylene derivative; 5-Chloro-3-phenyl-1H-indole-2-carboxylic acid dimethylaminomethyleneamide; 338401-01-7; 5-Chloro-N-[(dimethylamino)methylidene]-3-phenyl-1H-indole-2-carboxamide; (5-Chloro-3-phenyl-1H-indol-2-yl)-N-[(dimethylamino)methylidene]formamide
EINECS	Contact for details

Quality Control

Our 5-Chloro-n-[(Dimethylamino)Methylene]-3-Phenyl-1H-Indole-2-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.