Description

[1-(Bromomethyl)Cyclopropyl]Acetonitrile is a versatile and highly functionalized organic building block, featuring both a reactive bromomethyl group and a nitrile moiety. This compound is critical for the synthesis of complex molecules, enabling the efficient construction of cyclopropane-containing scaffolds and the introduction of further functional groups. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for constructing cyclopropane rings in drug discovery, particularly for protease inhibitors, kinase inhibitors, and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the cyclopropane unit can enhance biological activity.
• Material Science Research: Serves as a precursor for specialty polymers and advanced organic materials with tailored properties.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and labeled compounds for studying biological mechanisms.
• Cross-Coupling Reactions: The bromomethyl group acts as an electrophile in various metal-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi).
• Nitrile Transformation: The nitrile functionality can be hydrolyzed to carboxylic acids, reduced to amines, or used in heterocycle formation (e.g., tetrazoles).

Basic Information

Product Name	[1-(Bromomethyl)Cyclopropyl]Acetonitrile
CAS No.	338392-48-6
Molecular Formula	C6H8BrN
Molecular Weight	174.04 g/mol
Synonyms	(1-(Bromomethyl)cyclopropyl)acetonitrile; 2-[1-(Bromomethyl)cyclopropyl]acetonitrile; 1-(Bromomethyl)cyclopropaneacetonitrile; Cyclopropaneacetonitrile, 1-(bromomethyl)-; (1-Bromomethyl-cyclopropyl)-acetonitrile
EINECS	Contact for details

Quality Control

Our [1-(Bromomethyl)Cyclopropyl]Acetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.