Description

4-Fluoro-3-(Methoxymethyl)Phenylboronic Acid is a versatile and high-value boronic acid derivative, essential for modern synthetic chemistry. Its primary value lies in its role as a key coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is critically needed by R&D and production teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing active pharmaceutical ingredients (APIs), particularly those containing fluorinated biaryl motifs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring specific fluorinated aromatic structures.
• Material Science Research: Serves as a monomer or precursor in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Suzuki-Miyaura Cross-Coupling: The principal application is as a boronic acid reagent in palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Chemical Biology & Medicinal Chemistry: Employed in the synthesis of molecular probes, diagnostic agents, and compound libraries for drug discovery screening.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Product Name	4-Fluoro-3-(Methoxymethyl)Phenylboronic Acid
CAS No.	337536-19-3
Molecular Formula	C8H10BFO3
Molecular Weight	183.98 g/mol
Synonyms	(4-Fluoro-3-(methoxymethyl)phenyl)boronic acid; 3-Methoxymethyl-4-fluorophenylboronic acid; 4-Fluoro-3-methoxymethylbenzeneboronic acid; B-[4-Fluoro-3-(methoxymethyl)phenyl]boronic acid; 4-Fluoro-3-(methoxymethyl)benzeneboronic acid; (4-Fluoro-3-methoxymethylphenyl)boronic acid
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-(Methoxymethyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive coupling reactions. Certificates of Analysis (COA) with detailed chromatographic data are available for every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged use or when opening a new container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.