Description

Methyl 2-Fluoro-4-Nitrophenylacetate is a specialized fluorinated aromatic ester, serving as a crucial synthetic intermediate in advanced organic chemistry. Its value lies in the strategic combination of a fluorine atom and a nitro group on the phenyl ring, which are key functional handles for further chemical transformations. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly in the synthesis of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of fluorinated drug candidates, leveraging the fluorine atom for metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, pesticides, and fungicides where the nitro and fluoro substituents impart specific biological activity.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and advanced organic materials with tailored properties.
• Chemical Research & Development: Employed in academic and industrial labs for methodological studies in cross-coupling reactions, nucleophilic aromatic substitution, and other fluorochemistry applications.
• Dye and Pigment Intermediate: Acts as a precursor in the synthesis of complex fluorinated dyes and specialty colorants.

Basic Information

Product Name	Methyl 2-Fluoro-4-Nitrophenylacetate
CAS No.	337529-74-5
Molecular Formula	C9H8FNO4
Molecular Weight	213.16 g/mol
Synonyms	Methyl (2-Fluoro-4-nitrophenyl)acetate; Acetic acid, 2-(2-fluoro-4-nitrophenyl)-, methyl ester; 2-Fluoro-4-nitrophenylacetic acid methyl ester; Methyl α-(2-fluoro-4-nitrophenyl)acetate; (2-Fluoro-4-nitrophenyl)acetic acid methyl ester; Methyl 2-fluoro-4-nitrobenzeneacetate; 337529-74-5
EINECS	Contact for details

Quality Control

Our Methyl 2-Fluoro-4-Nitrophenylacetate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with detailed results from techniques such as HPLC, GC, NMR, and IR spectroscopy. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable performance in your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.