Description

L-Alanine, 3-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-, Methyl Ester is a sophisticated, protected amino acid derivative designed for advanced synthetic applications. This compound is critical for researchers and manufacturers requiring high-purity, custom building blocks for complex organic synthesis, particularly in peptide chemistry. It is primarily utilized in the pharmaceutical and biotechnology sectors for the development of novel therapeutic peptides and active pharmaceutical ingredients (APIs). Its specific protection groups offer precise control over synthetic pathways, making it an essential reagent for specialized R&D and production.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a key Fmoc/Boc-protected alanine derivative for the controlled assembly of custom peptide sequences.
• Pharmaceutical Intermediate: Used in the research and development of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Bioconjugation and Labeling: Acts as a specialized linker or precursor for attaching peptides to other molecules, such as dyes, polymers, or drug delivery systems.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to discover new bioactive compounds.
• Academic and Industrial R&D: A fundamental reagent for synthetic organic chemistry research focused on amino acid and peptide methodology.
• Protecting Group Chemistry: Demonstrates the orthogonal use of Fmoc and Boc protecting groups, useful for teaching and advanced synthesis strategies.

Basic Information

Product Name	L-Alanine, 3-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-, Methyl Ester
CAS No.	336854-66-1
Molecular Formula	C24H28N2O6
Molecular Weight	440.49 g/mol
Synonyms	Fmoc-N-Boc-L-alanine methyl ester; (S)-Methyl 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-((tert-butoxycarbonyl)amino)propanoate; N-α-Fmoc-N-β-Boc-L-diaminopropionic acid methyl ester; Boc-Dap(Fmoc)-OMe; Fmoc-L-BocDap-OH methyl ester; Nα-Fmoc-Nβ-Boc-L-2,3-diaminopropionic acid methyl ester; L-2,3-Diaminopropionic acid, N2-[(1,1-dimethylethoxy)carbonyl]-N3-[(9H-fluoren-9-ylmethoxy)carbonyl]-, methyl ester
EINECS	Contact for details

Quality Control

Our L-Alanine, 3-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for pharmaceutical research and synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]D20	Contact for details
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.