Description

1-Methoxymethoxy-2-(Trifluoromethyl)Benzene is a versatile fluorinated aromatic building block featuring a protected hydroxyl group. This compound is valued for its unique reactivity, serving as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on active ingredients, advanced materials, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial synthon for constructing active pharmaceutical ingredients (APIs), especially those requiring trifluoromethyl-substituted aromatic cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for specialized ligands in catalysis and as a building block for functional materials.
• Organic Synthesis & Process Chemistry: Employed in cross-coupling reactions, nucleophilic substitutions, and as a protected phenol equivalent in multi-step synthetic routes.
• Material Science Research: Used in the synthesis of monomers or additives for advanced polymers with specific optical or electronic properties.

Basic Information

Product Name	1-Methoxymethoxy-2-(Trifluoromethyl)Benzene
CAS No.	336628-65-0
Molecular Formula	C10H11F3O2
Molecular Weight	220.19 g/mol
Synonyms	2-(Trifluoromethyl)phenyl methoxymethyl ether; 1-Methoxymethoxy-2-(trifluoromethyl)benzene; o-(Trifluoromethyl)phenyl methoxymethyl ether; MOM ether of 2-(Trifluoromethyl)phenol; (2-(Trifluoromethyl)phenoxymethoxy)methane; Benzene, 1-methoxymethoxy-2-(trifluoromethyl)-; 2-(Methoxymethoxy)benzotrifluoride
EINECS	Contact for details

Quality Control

Our 1-Methoxymethoxy-2-(Trifluoromethyl)Benzene is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids, strong bases, and oxidizing agents. Due to its properties, it is recommended to store at controlled room temperature (15-25°C) under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.