Description

Boc-L-β-Homoasparagine is a protected amino acid derivative of significant importance in advanced organic synthesis and peptide chemistry. This compound serves as a crucial building block for the controlled introduction of the β-homoasparagine moiety into complex molecular structures, enabling the exploration of modified peptide backbones. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel peptide-based therapeutics, peptidomimetics, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the incorporation of β-homoasparagine into peptide chains, allowing for backbone modification and structure-activity relationship (SAR) studies.
• Peptidomimetic Drug Discovery: Used in the design and synthesis of peptide analogs with enhanced metabolic stability, bioavailability, and receptor selectivity.
• Bioconjugation and Labeling: The reactive functional groups make it suitable for creating labeled peptides or conjugating peptides to other molecules, such as fluorophores or polymers.
• Academic and Industrial Research: Serves as a valuable reagent in chemical biology for probing enzyme function and protein-protein interactions.
• Combinatorial Chemistry Libraries: Employed as a diverse building block to generate libraries of novel compounds for high-throughput screening.

Basic Information

Product Name	Boc-L-β-Homoasparagine
CAS No.	336182-03-7
Molecular Formula	C10H18N2O6
Molecular Weight	262.26 g/mol
Synonyms	(2S)-4-Amino-2-[[(2-methylpropan-2-yl)oxycarbonyl]amino]-4-oxobutanoic acid; Nα-Boc-L-β-homoasparagine; Boc-L-β-homo-Asn-OH; tert-Butyloxycarbonyl-L-β-homoasparagine; (S)-2-((tert-Butoxycarbonyl)amino)-4-amino-4-oxobutanoic acid; Boc-β-hAsn-OH; N-Boc-L-β-homoasparagine
EINECS	Contact for details

Quality Control

Our Boc-L-β-Homoasparagine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for sensitive research and development applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.