Description

4-Fluoro-2-(Methoxymethoxy)Phenylboronic Acid CAS NO 335254-87-0 is a specialized organoboron compound that serves as a crucial building block in modern synthetic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This high-purity intermediate is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers for the synthesis of active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those containing fluorinated biaryl motifs for enhanced metabolic stability and bioavailability.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a critical boronic acid reagent for forming carbon-carbon bonds between aromatic rings, a fundamental step in medicinal chemistry and material science.
• Ligand and Catalyst Development: Used in the research and production of specialized ligands and organometallic catalysts.
• Agrochemical Synthesis: Employed in the development of advanced, fluorinated active ingredients for crop protection products.
• Material Science Research: Utilized in the creation of organic electronic materials, such as those for OLEDs and semiconductors, where specific fluorinated architectures are required.
• Chemical Biology Probes: Acts as a building block for fluorescent tags and molecular probes used in diagnostic and research applications.

Basic Information

Product Name	4-Fluoro-2-(Methoxymethoxy)Phenylboronic Acid
CAS No.	335254-87-0
Molecular Formula	C9H12BFO4
Molecular Weight	214.00 g/mol
Synonyms	[4-Fluoro-2-(methoxymethoxy)phenyl]boronic acid; (4-Fluoro-2-methoxymethoxyphenyl)boronic acid; 2-MOM-4-Fluorophenylboronic Acid; 4-Fluoro-2-MOM-phenylboronic acid; Boronic acid, B-[4-fluoro-2-(methoxymethoxy)phenyl]-; 4-Fluoro-2-(MOMoxy)phenylboronic Acid
EINECS	Contact for details

Quality Control

Every batch of 4-Fluoro-2-(Methoxymethoxy)Phenylboronic Acid is produced under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for demanding synthetic applications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.