Description

-Iodoresiniferatoxin CAS NO 335151-55-8 is a potent and selective vanilloid receptor (TRPV1) antagonist, a high-value chemical tool for advanced pharmacological research. Its core value lies in enabling precise investigation of pain signaling pathways and neurogenic inflammation mechanisms. This compound is essential for pharmaceutical R&D teams, academic neuroscientists, and contract research organizations (CROs) focused on developing novel analgesics and treatments for chronic pain conditions.

Application

• Pharmacological Research: A critical tool for studying the structure and function of the transient receptor potential vanilloid 1 (TRPV1) channel.
• Neuroscience Studies: Used to investigate pain perception, neurogenic inflammation, and thermal sensation pathways in both in vitro and in vivo models.
• Drug Discovery & Development: Serves as a reference standard and a key intermediate in the development of novel TRPV1-targeted therapeutics for chronic pain management.
• Biochemical Assays: Employed in high-throughput screening (HTS) and functional assays to identify and characterize new TRPV1 modulators.
• Academic Research: Utilized in university and institutional labs for fundamental research into ion channel physiology and pharmacology.

Basic Information

Product Name	-Iodoresiniferatoxin
CAS No.	335151-55-8
Molecular Formula	C24H27IO6
Molecular Weight	538.38 g/mol
Synonyms	Iodo-resiniferatoxin; I-RTX; (E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-(iodomethyl)-N-nonylnon-6-enamide; 5'-Iodoresiniferatoxin; 6-Iodomethyl-8-methylnon-6-enoyl vanillylamide; TRPV1 antagonist I-RTX; Iodinated resiniferatoxin analog
EINECS	Contact for details

Quality Control

Our -Iodoresiniferatoxin is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity determination and spectroscopic methods for structural confirmation. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.