Description

n-{4-[(1,3-Benzodioxol-5-Ylamino)Sulfonyl]Phenyl}Acetamide is a specialized sulfonamide derivative featuring a benzodioxole moiety, making it a valuable synthetic intermediate for advanced organic synthesis. This compound is critical for research and development in the pharmaceutical and agrochemical sectors, where its unique structure serves as a key building block for creating novel active molecules. It is primarily sought by R&D chemists and process development scientists working on new drug candidates, crop protection agents, and other fine chemical applications requiring precise molecular architecture.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential new chemical entities (NCEs) for drug discovery programs, particularly those targeting enzymes or receptors where the sulfonamide pharmacophore is relevant.
• Agrochemical Research: Used as a building block in the development of novel herbicides, fungicides, or insecticides, leveraging the benzodioxole group for enhanced biological activity and metabolic stability.
• Chemical Biology Probe: Employed in academic and industrial research to create molecular probes for studying biological pathways and protein functions.
• Material Science Applications: Potential use in the synthesis of specialty polymers or advanced materials where specific sulfonamide linkages are required.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules on a laboratory to pilot scale.

Basic Information

Product Name	n-{4-[(1,3-Benzodioxol-5-Ylamino)Sulfonyl]Phenyl}Acetamide
CAS No.	333747-86-7
Molecular Formula	C15H14N2O5S
Molecular Weight	334.35 g/mol
Synonyms	N-[4-[(1,3-Benzodioxol-5-ylamino)sulfonyl]phenyl]acetamide; 4'-Acetamidobenzenesulfonamide, N-(1,3-benzodioxol-5-yl)-; 4-Acetamidobenzenesulfonamide, N-(1,3-benzodioxol-5-yl)-; 1,3-Benzodioxole-5-sulfonamide, N-[4-(acetylamino)phenyl]-; N-(4-Acetamidophenyl)-1,3-benzodioxole-5-sulfonamide; 333747-86-7; 4-Acetamido-N-(1,3-benzodioxol-5-yl)benzenesulfonamide
EINECS	Contact for details

Quality Control

Our n-{4-[(1,3-Benzodioxol-5-Ylamino)Sulfonyl]Phenyl}Acetamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, which include data for critical parameters such as assay, related substances, and residual solvents. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable and reproducible performance in your downstream synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.