Description

Fmoc-2-Amino-5-Methylbenzoic Acid is a high-purity, protected amino acid derivative essential for solid-phase peptide synthesis (SPPS). This compound serves as a critical building block for the controlled introduction of a modified tyrosine or phenylalanine analogue into peptide chains, enabling advanced research and pharmaceutical development. It is primarily utilized by research institutions, biotechnology companies, and pharmaceutical manufacturers engaged in peptide-based drug discovery, proteomics, and the synthesis of complex biomolecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key Fmoc-protected amino acid for the automated synthesis of custom peptides and peptide libraries.
• Pharmaceutical Intermediate: Used in the research and development of novel therapeutic peptides and peptidomimetics.
• Bioconjugation: Acts as a versatile linker or spacer molecule for attaching peptides to other biomolecules, surfaces, or carriers.
• Chemical Biology Probes: Incorporated into peptides used as tools for studying protein-protein interactions and enzyme activity.
• Material Science: Employed in the synthesis of peptide-based polymers and advanced biomaterials.

Basic Information

Product Name	Fmoc-2-Amino-5-Methylbenzoic Acid
CAS No.	332121-91-2
Molecular Formula	C23H19NO4
Molecular Weight	373.40 g/mol
Synonyms	Fmoc-2-Amino-5-methylbenzoic acid; 2-[(9H-Fluoren-9-ylmethoxy)carbonyl]amino-5-methylbenzoic acid; N-Fmoc-2-amino-5-methylbenzoic acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]anthranilic acid, 5-methyl-; Fmoc-5-methylanthranilic acid; 5-Methyl-Fmoc-anthranilic acid; 2-(Fmoc-amino)-5-methylbenzoic acid
EINECS	Contact for details

Quality Control

Our Fmoc-2-Amino-5-Methylbenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive peptide synthesis applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.