Description

n-De(4-Sulfonamidophenyl)-N'-(4-Sulfonamidophenyl) Celecoxib is a high-purity, synthetic chemical intermediate derived from the celecoxib structure, specifically designed for advanced pharmaceutical research and development. This compound is critical for medicinal chemists exploring novel COX-2 inhibitor derivatives and other therapeutic agents targeting inflammation and related pathways. It serves as a key building block for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require precise, well-characterized intermediates for drug discovery and process development.

Application

• Pharmaceutical Intermediate: Primary use as a sophisticated building block in the synthesis of next-generation COX-2 inhibitors and related anti-inflammatory drug candidates.
• Medicinal Chemistry Research: Enables structure-activity relationship (SAR) studies and lead optimization programs focused on sulfonamide-based therapeutics.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in API (Active Pharmaceutical Ingredient) manufacturing.
• Biochemical Tool Compound: Used in vitro and in vivo studies to investigate cyclooxygenase enzyme mechanisms and inflammatory pathways.
• Fine Chemical Synthesis: A precursor for creating specialized, high-value compounds for contract research and custom synthesis projects.

Basic Information

Product Name	n-De(4-Sulfonamidophenyl)-N'-(4-Sulfonamidophenyl) Celecoxib
CAS No.	331943-04-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	4,4'-(5-Phenyl-3-(trifluoromethyl)-1H-pyrazol-1,4-diyl)dibenzenesulfonamide; Celecoxib bis-sulfonamide derivative; N,N'-Bis(4-sulfamoylphenyl)celecoxib derivative; 1,4-Bis(4-sulfonamidophenyl)-5-phenyl-3-(trifluoromethyl)pyrazole; Celecoxib disulfonamide analog
EINECS	Contact for details

Quality Control

Our n-De(4-Sulfonamidophenyl)-N'-(4-Sulfonamidophenyl) Celecoxib is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.