Description

(S)-3-Amino-4-(Pentafluorophenyl)-Butyric Acid-Hcl CAS NO 331847-07-5 is a high-purity, non-natural amino acid derivative characterized by its chiral (S)-configuration and a pentafluorophenyl side chain. This compound matters as a sophisticated chiral building block, enabling the synthesis of complex molecules with precise stereochemistry for advanced research and development. It is primarily needed by pharmaceutical and agrochemical R&D teams for applications in medicinal chemistry, including the development of enzyme inhibitors and novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs), particularly for targeted therapies.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and as a building block for protease inhibitors and other enzyme-targeted compounds.
• Agrochemical Research: Serves as a precursor in the synthesis of advanced, chiral agrochemicals with specific biological activity.
• Peptidomimetics: Incorporated into peptide analogs to enhance metabolic stability, bioavailability, and binding affinity.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein function.
• Asymmetric Synthesis: Acts as a chiral pool starting material or auxiliary for the construction of complex, enantiomerically pure molecules.

Basic Information

Product Name	(S)-3-Amino-4-(Pentafluorophenyl)-Butyric Acid-Hcl
CAS No.	331847-07-5
Molecular Formula	C10H9F5NO2 • HCl
Molecular Weight	311.64 (Free base) / 348.10 (HCl salt)
Synonyms	(S)-3-Amino-4-(pentafluorophenyl)butanoic acid hydrochloride; (S)-3-Amino-4-(2,3,4,5,6-pentafluorophenyl)butyric acid HCl; (S)-4-(Pentafluorophenyl)-3-aminobutanoic acid hydrochloride; (3S)-3-Amino-4-(2,3,4,5,6-pentafluorophenyl)butanoic acid hydrochloride; Pentafluorophenylalanine derivative; (S)-3-Amino-4-(C6F5)butyric acid HCl; F5Phe derivative
EINECS	Contact for details

Quality Control

Our (S)-3-Amino-4-(Pentafluorophenyl)-Butyric Acid-Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-purity research-grade standards. Certificates of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.