Description

Benzyl 2-(5-Bromo-1H-Indole-3-Carbonyl)Pyrrolidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate designed for complex organic synthesis. This compound is critical for research and development in medicinal chemistry, serving as a versatile building block for novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its reactive indole and pyrrolidine moieties.
• API Development: Serves as a precursor in the multi-step synthesis of complex, high-value active pharmaceutical ingredients.
• Biochemical Research: Employed as a tool compound in biochemical assays and for probing enzyme-substrate interactions.
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) specializing in bespoke, small-molecule synthesis.

Basic Information

Product Name	Benzyl 2-(5-Bromo-1H-Indole-3-Carbonyl)Pyrrolidine-1-Carboxylate
CAS No.	331842-86-5
Molecular Formula	C21H19BrN2O3
Molecular Weight	427.29 g/mol
Synonyms	1-[(Benzyloxy)carbonyl]-2-[(5-bromo-1H-indol-3-yl)carbonyl]pyrrolidine; Benzyl 2-(5-Bromoindole-3-carbonyl)pyrrolidine-1-carboxylate; 5-Bromo-1H-indole-3-carboxylic acid (1-benzyloxycarbonylpyrrolidin-2-yl)amide; 331842-86-5; 1-CBz-2-(5-Bromo-1H-indole-3-carbonyl)pyrrolidine; (1-Benzyloxycarbonylpyrrolidin-2-yl)-(5-bromo-1H-indol-3-yl)methanone
EINECS	Contact for details

Quality Control

Our Benzyl 2-(5-Bromo-1H-Indole-3-Carbonyl)Pyrrolidine-1-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.