Description

n-(3-Aminophenyl)-4-tert-Butylbenzamide is a high-purity aromatic amide derivative featuring both an aniline and a tert-butylbenzamide moiety. This compound serves as a versatile and critical pharmaceutical intermediate and organic synthesis building block for constructing complex molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce specific steric and electronic properties into their target compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammatory pathways.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and fungicides, where the tert-butyl group can enhance lipophilicity and biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis, useful in asymmetric synthesis.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for engineering polymers with enhanced thermal stability and specific interactive sites.
• Dye and Pigment Intermediate: Employed in the synthesis of advanced colorants and optical materials due to its conjugated aromatic structure.
• Research & Development: A valuable tool compound in academic and industrial laboratories for method development and exploring new chemical spaces in medicinal chemistry.

Basic Information

Product Name	n-(3-Aminophenyl)-4-tert-Butylbenzamide
CAS No.	330997-09-6
Molecular Formula	C17H20N2O
Molecular Weight	268.36 g/mol
Synonyms	4-tert-Butyl-N-(3-aminophenyl)benzamide; 3-Amino-N-(4-tert-butylbenzoyl)aniline; N-(3-Aminophenyl)-4-(tert-butyl)benzamide; 4-(tert-Butyl)-N-(3-aminophenyl)benzamide; Benzoic acid, 4-(1,1-dimethylethyl)-, 3-aminophenylamide; 330997-09-6; 4-tert-Butylbenzoic acid (3-aminophenyl)amide
EINECS	Contact for details

Quality Control

Our n-(3-Aminophenyl)-4-tert-Butylbenzamide is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the high standards required for GMP-grade intermediates and sensitive R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.