Description

4-Bromo-2-Methoxy-Benzonitrile is a versatile aromatic nitrile building block characterized by its bromine and methoxy substituents. This compound is critical for facilitating advanced organic synthesis, particularly in the construction of complex pharmaceutical intermediates and agrochemicals. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a substituted benzonitrile core.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides, where the bromine atom serves as a handle for further functionalization.
• Ligand and Catalyst Development: Employed in organic and organometallic chemistry to create novel ligands for catalysis and material science applications.
• Material Science Research: Serves as a building block for organic electronic materials, liquid crystals, and advanced polymers.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Buchwald-Hartwig aminations.
• Chemical Biology Probes: Used in the design and synthesis of molecular probes for studying biological systems and enzyme mechanisms.

Basic Information

Product Name	4-Bromo-2-Methoxy-Benzonitrile
CAS No.	330793-38-9
Molecular Formula	C8H6BrNO
Molecular Weight	212.05 g/mol
Synonyms	4-Bromo-2-methoxybenzonitrile; 2-Methoxy-4-bromobenzonitrile; Benzonitrile, 4-bromo-2-methoxy-; 4-Bromo-o-anisonitrile; 4-Bromo-2-methoxy-phenyl cyanide
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Methoxy-Benzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.