Description

3-Bromo-5-Ethoxy-4-Hydroxy-Benzonitrile is a versatile benzonitrile derivative that serves as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for constructing complex molecules with specific electronic and steric properties. This compound is primarily sought after by research institutions and chemical manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound libraries.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the bromo and ethoxy groups enable targeted bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and other functional organic materials due to its electron-withdrawing nitrile group.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and fluorescent tags for biological imaging and diagnostic applications.

Basic Information

Product Name	3-Bromo-5-Ethoxy-4-Hydroxy-Benzonitrile
CAS No.	330462-57-2
Molecular Formula	C9H8BrNO2
Molecular Weight	242.07 g/mol
Synonyms	4-Hydroxy-3-bromo-5-ethoxybenzonitrile; 5-Ethoxy-4-hydroxy-3-bromobenzonitrile; Benzonitrile, 3-bromo-5-ethoxy-4-hydroxy-; 3-Bromo-5-ethoxy-4-hydroxybenzonitrile; 330462-57-2
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Ethoxy-4-Hydroxy-Benzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed results from techniques including HPLC, NMR, and IR spectroscopy. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.