Description

Tau Peptide (298-312) CAS NO 330456-47-8 is a synthetic peptide fragment corresponding to amino acid residues 298-312 of the human tau protein. This sequence-specific peptide is a critical research tool for studying tauopathies, including Alzheimer's disease and other neurodegenerative disorders. It is primarily utilized by researchers and developers in neuroscience, pharmaceutical R&D, and diagnostic assay development to investigate protein aggregation, antibody specificity, and therapeutic mechanisms.

Application

• Neuroscience Research: Fundamental studies on tau protein biochemistry, phosphorylation, and aggregation kinetics.
• Antibody Development & Validation: Serves as a key antigen for generating and characterizing tau-specific monoclonal and polyclonal antibodies.
• Diagnostic Assay Development: Used as a coating antigen or standard in ELISA, Western blot, and other immunoassays for detecting tau-related biomarkers.
• Drug Discovery Screening: A target compound in high-throughput screening assays to identify potential inhibitors of tau aggregation or misfolding.
• Biomarker Studies: Investigation of tau fragments as potential cerebrospinal fluid (CSF) or blood-based biomarkers for disease progression.
• Academic & Institutional Research: Supports basic and translational research in university and hospital laboratories worldwide.

Basic Information

Product Name	Tau Peptide (298-312)
CAS No.	330456-47-8
Molecular Formula	C73H118N22O23S
Molecular Weight	1687.9 g/mol
Synonyms	Tau Protein (298-312); Human Tau (298-312) Peptide; Tau 298-312; Microtubule-associated protein tau (298-312); MAPT (298-312); H-TKKPSSGEPPKSGDR-OH; Phosphorylation Site Peptide (if applicable); Alzheimer's Disease Research Peptide
EINECS	Contact for details

Quality Control

Our Tau Peptide (298-312) is manufactured under stringent conditions to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to ISO 9001 quality management principles, and our production processes are designed to meet the exacting standards required for life science research. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store the lyophilized powder desiccated at -20°C. Reconstituted solutions should be aliquoted and stored at -20°C or -80°C to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 70% (by weight)
Amino Acid Analysis	Within ± 10% of theoretical
Solubility	Soluble in water or dilute acetic acid
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 8.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.