Description

Tau Peptide (295-309) CAS NO 330456-46-7 is a synthetic peptide fragment corresponding to amino acid residues 295-309 of the human tau protein. This specific sequence is of significant interest in neurological research for studying protein aggregation mechanisms and tauopathies. It serves as a critical research tool for pharmaceutical, biotechnology, and academic laboratories focused on neurodegenerative diseases such as Alzheimer's.

Application

• Biomedical Research: Primary tool for studying tau protein biochemistry, phosphorylation, and aggregation pathways in vitro.
• Antibody Development & Epitope Mapping: Used as an antigen for generating and characterizing monoclonal and polyclonal antibodies specific to the tau protein.
• Diagnostic Assay Development: Serves as a key component in the development of immunoassays (ELISA, Western Blot) for detecting tau-related biomarkers.
• Drug Discovery Screening: Employed in high-throughput screening platforms to identify potential therapeutic compounds that inhibit abnormal tau aggregation.
• Neuroscience Studies: Fundamental reagent for investigating the role of specific tau domains in neuronal function and dysfunction.
• Quality Control Reference Standard: Used as a reference material for the quality control of tau protein-based reagents and diagnostic kits.

Basic Information

Product Name	Tau Peptide (295-309)
CAS No.	330456-46-7
Molecular Formula	C73H122N22O23S
Molecular Weight	1684.0 g/mol
Synonyms	Tau (295-309) Peptide; Tau Protein Fragment 295-309; Human Tau (295-309); H-TKSPVVSGDTSPRHL-NH2; Acetyl-TKSPVVSGDTSPRHL-amide; Microtubule-associated protein tau (295-309); MAPT (295-309); Neurofibrillary tangle peptide fragment
EINECS	Contact for details

Quality Control

Our Tau Peptide (295-309) is manufactured under stringent conditions to ensure the highest standards of purity and batch-to-batch consistency for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity assessment and Mass Spectrometry (MS) for identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, amino acid analysis, and other critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture absorption. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Amino Acid Composition	Within ± 10% of theoretical values
Net Peptide Content	≥ 80%
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.