Description

Tau Peptide (306-336) (Repeat 3 Domain) CAS NO 330456-26-3 is a synthetic peptide fragment corresponding to a specific repeat region of the human tau protein. This compound is a critical research tool for investigating the molecular mechanisms underlying tauopathies, including Alzheimer's disease. It is primarily utilized by pharmaceutical R&D teams, academic neuroscientists, and diagnostic developers for applications in biochemical assays, antibody development, and neurodegenerative disease modeling.

Application

• Neuroscience Research: Fundamental studies on tau protein aggregation, phosphorylation, and microtubule binding dynamics.
• Therapeutic Target Validation: Screening and characterization of potential drug candidates designed to inhibit pathological tau aggregation.
• Diagnostic Antibody Development: Serving as a key antigen for the production and testing of selective antibodies used in immunoassays and imaging.
• Biomarker Discovery: Use in assay development to detect and quantify specific tau isoforms or fragments in biological samples.
• Cell Culture & In Vitro Models: Induction of tau-related pathology in cellular models of neurodegeneration.
• Quality Control Reference Standard: Acting as a qualified reference material in the quality control of tau-related diagnostic kits and reagents.

Basic Information

Product Name	Tau Peptide (306-336) (Repeat 3 Domain)
CAS No.	330456-26-3
Molecular Formula	C140H238N44O49S
Molecular Weight	~3170.7 g/mol
Synonyms	Tau Protein Fragment (306-336); Microtubule-Associated Protein Tau (306-336); Tau Repeat Domain Peptide (R3); hTau(306-336); MAPT (306-336); Tau Peptide R3; Synthetic Tau Peptide; Alzheimer's Disease Tau Peptide
EINECS	Contact for details

Quality Control

Our Tau Peptide (306-336) is manufactured under stringent conditions to ensure batch-to-batch consistency and high biological activity. Quality is verified through a comprehensive suite of analytical techniques, including reverse-phase HPLC for purity assessment and mass spectrometry (MS) for identity confirmation. Certificates of Analysis (COA) detailing purity, peptide content, and analytical data are provided with each shipment to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (MS)	Consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Peptide Content	≥ 70% (by weight)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water or aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.