Description

2-Propenenitrile,3-(2-Fluoro-4-Pyridinyl)-(9Ci) is a specialized fluorinated pyridine derivative and a key nitrile-based building block in advanced organic synthesis. This compound matters for its role as a crucial intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique structure enables precise molecular modifications. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor research and other targeted therapies.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, leveraging its fluoropyridine moiety for enhanced bioactivity.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced materials with specific electronic or photonic properties.
• Chemical Biology Probes: Utilized to create labeled compounds and probes for studying biological mechanisms and target engagement.

Basic Information

Product Name	2-Propenenitrile,3-(2-Fluoro-4-Pyridinyl)-(9Ci)
CAS No.	329974-14-3
Molecular Formula	C8H5FN2
Molecular Weight	148.14 g/mol
Synonyms	3-(2-Fluoro-4-pyridinyl)-2-propenenitrile; 2-Fluoro-4-(2-cyanoethenyl)pyridine; (E)-3-(2-Fluoropyridin-4-yl)acrylonitrile; 2-Fluoro-4-trans-cyanovinylpyridine; 4-(2-Cyanoethenyl)-2-fluoropyridine; Acrylonitrile, 3-(2-fluoro-4-pyridinyl)-; 329974-14-3
EINECS	Contact for details

Quality Control

Our production of 2-Propenenitrile,3-(2-Fluoro-4-Pyridinyl)-(9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We are committed to meeting the exacting standards required for pharmaceutical intermediate use, with specifications available to support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.