Description

Dichloro[(R)-(+)-2,2'-Bis(Diphenylphosphino)-1,1'-Binaphthyl][(1R,2R)-(+)-1,2-Diphenylethylenediamine]Ruthenium (II) is a highly specialized chiral ruthenium complex, recognized as a premier catalyst for asymmetric hydrogenation and transfer hydrogenation reactions. Its value lies in enabling the synthesis of enantiomerically pure intermediates, which are critical for the production of high-value pharmaceuticals and fine chemicals. This product is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require exceptional stereoselectivity and catalytic efficiency.

Application

• Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of ketones, imines, and functionalized olefins to produce chiral alcohols, amines, and other building blocks.
• Pharmaceutical Intermediate Synthesis: Key for manufacturing active pharmaceutical ingredients (APIs) requiring high enantiomeric purity, such as certain antibiotics, antivirals, and cardiovascular drugs.
• Agrochemical Production: Used in the synthesis of chiral herbicides, fungicides, and plant growth regulators.
• Fine Chemical and Fragrance Manufacturing: Enables the production of enantiomerically pure flavors, fragrances, and specialty chemicals.
• Academic and Industrial R&D: A valuable tool for methodological development in organic synthesis and catalysis research.
• Transfer Hydrogenation Reactions: Employed in reactions using alternative hydrogen donors like isopropanol or formic acid.

Basic Information

Item	Detail
Product Name	Dichloro[(R)-(+)-2,2'-Bis(Diphenylphosphino)-1,1'-Binaphthyl][(1R,2R)-(+)-1,2-Diphenylethylenediamine]Ruthenium (II)
CAS No.	329735-87-7
Molecular Formula	C52H44Cl2N2P2Ru
Molecular Weight	932.86 g/mol
Synonyms	RuCl2[(R)-BINAP][(R,R)-DPEN]; (R,R)-Ru-BINAP-DPEN Dichloride; Noyori-Ikariya Catalyst; [RuCl2((R)-binap)((R,R)-dpen)]; Ruthenium(II) (R)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl (1R,2R)-1,2-Diphenylethylenediamine Dichloride; Asymmetric Hydrogenation Catalyst 329735-87-7; (R)-BINAP/(R,R)-DPEN Ru(II) Complex
EINECS	Contact for details

Quality Control

Every batch of our chiral ruthenium catalyst is produced and tested under strict quality protocols to ensure consistent high performance and purity for critical asymmetric synthesis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as chiral purity, metal content, and specific catalytic activity. Our quality system is designed to support cGMP and ISO standards for pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to maintain stability and prevent decomposition. The container should be kept in a cool, dry, and well-ventilated area, separate from incompatible materials.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Ruthenium Content	10.5 - 11.5 %
Solubility	Soluble in dichloromethane, toluene; slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.