Description

2-(Trifluoromethoxy)Ethyl Trifluoromethanesulfonate is a specialized fluorinated organic sulfonate ester, a key reagent in advanced chemical synthesis. Its primary value lies in its dual functionality as a powerful alkylating agent and a source of the trifluoromethanesulfonate (triflate) group, enabling critical transformations in complex molecule construction. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the synthesis of active ingredients and novel materials requiring robust fluorine incorporation.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs), leveraging the triflate group for efficient C-O and C-C bond formation.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the trifluoromethoxy and triflate moieties enhance biological activity and metabolic stability.
• Ligand and Catalyst Preparation: Serves as a precursor for generating specialized ligands and organometallic catalysts used in cross-coupling reactions and asymmetric synthesis.
• Material Science: Employed in the development of fluorinated polymers, liquid crystals, and electronic materials to modify surface properties and stability.
• Organic Synthesis Reagent: Functions as a versatile reagent for introducing the 2-(trifluoromethoxy)ethyl group into complex molecular architectures under mild conditions.

Basic Information

Product Name	2-(Trifluoromethoxy)Ethyl Trifluoromethanesulfonate
CAS No.	329710-76-1
Molecular Formula	C4H4F6O4S
Molecular Weight	262.13 g/mol
Synonyms	2-(Trifluoromethoxy)ethyl triflate; Trifluoromethanesulfonic acid 2-(trifluoromethoxy)ethyl ester; 2,2,2-Trifluoroethyl trifluoromethyl ether sulfonate; 1,1,1-Trifluoro-2-(trifluoromethoxy)ethanesulfonate; Ethanol, 2-(trifluoromethoxy)-, 1-trifluoromethanesulfonate; TFET; 2-TFMET
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethoxy)Ethyl Trifluoromethanesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, NMR, and Karl Fischer titration, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its nature as a strong acid/organic solvent, keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents. Use appropriate corrosion-resistant storage equipment.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Density (at 20°C)	~1.55 g/cm³
Refractive Index (n20D)	~1.35

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.