Description

Fmoc-Pea CAS NO 329223-23-6 is a high-purity, protected amino acid derivative widely used as a critical building block in solid-phase peptide synthesis (SPPS). Its primary value lies in enabling the controlled, sequential assembly of complex peptides and peptidomimetics for research and pharmaceutical development. This compound is essential for scientists and manufacturers in the fields of medicinal chemistry, biochemistry, and drug discovery who require reliable, high-quality intermediates for producing therapeutic peptides, diagnostic agents, and bioactive compounds.

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental building block for the Fmoc-strategy, used to incorporate specific amino acid sequences into target peptides.
• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of peptide-based active pharmaceutical ingredients (APIs) and investigational new drugs.
• Bioconjugation and Probe Development: Used to create labeled peptides for biochemical assays, imaging probes, and diagnostic tools.
• Medicinal Chemistry Research: Enables the exploration of structure-activity relationships (SAR) by facilitating the synthesis of novel peptide analogs.
• Production of Peptidomimetics: Employed in the design and synthesis of molecules that mimic the structure and function of natural peptides with improved stability.
• Academic and R&D Laboratories: A standard reagent for university and institutional research focused on protein engineering and molecular biology.

Basic Information

Product Name	Fmoc-Pea
CAS No.	329223-23-6
Molecular Formula	C20H21NO4
Molecular Weight	339.39 g/mol
Synonyms	Fmoc-PEA; Fmoc-β-homoPhe-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-phenyl-L-alanine; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-phenylpropanoic acid; Fmoc-L-homophenylalanine; Fmoc-3-phenyl-L-alanine; N-Fmoc-3-phenyl-L-alanine; Fmoc-Phe(3)-OH
EINECS	Contact for details

Quality Control

Our Fmoc-Pea is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, typically meeting standards suitable for pharmaceutical research and development. Every lot undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity. A Certificate of Analysis (COA) detailing specific results for identity, assay, and impurities is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Specific Rotation	-15.0° to -20.0° (c=1 in DMF)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.