Description

Ethanol, 2-[2-[4-(5-Oxidodibenzo[B,F][1,4]Thiazepin-11-Yl)-1-Piperazinyl]Ethoxy]- ,Dihydrochloride is a high-purity, complex organic salt primarily utilized as a key pharmaceutical intermediate. This compound matters for its role in the synthesis of advanced active pharmaceutical ingredients (APIs), where consistent quality and reliable supply are critical. It is needed by research institutions and manufacturers in the pharmaceutical and life sciences industries engaged in drug discovery and development.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel therapeutic agents, particularly in central nervous system (CNS) research.
• Chemical Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in laboratories.
• Research & Development: Serves as a starting material or precursor in medicinal chemistry programs for structure-activity relationship (SAR) studies.
• Active Pharmaceutical Ingredient (API) Synthesis: Employed in the multi-step synthesis of complex drug molecules requiring a high-purity, structurally defined intermediate.
• Biochemical Research: Potential use in pharmacological studies to investigate receptor binding and biochemical pathways.

Basic Information

Product Name	Ethanol, 2-[2-[4-(5-Oxidodibenzo[B,F][1,4]Thiazepin-11-Yl)-1-Piperazinyl]Ethoxy]- ,Dihydrochloride
CAS No.	329218-11-3
Molecular Formula	C21H26Cl2N2O3S
Molecular Weight	457.41 g/mol
Synonyms	11-[4-[2-(2-Hydroxyethoxy)ethyl]piperazin-1-yl]dibenzo[b,f][1,4]thiazepine 5-oxide dihydrochloride; Quetiapine Impurity; Quetiapine Related Compound; 2-[2-[4-(Dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl]ethoxy]ethanol S-oxide dihydrochloride; Quetiapine Metabolite Intermediate; DBZ 5-Oxide Dihydrochloride Derivative
EINECS	Contact for details

Quality Control

Our Ethanol, 2-[2-[4-(5-Oxidodibenzo[B,F][1,4]Thiazepin-11-Yl)-1-Piperazinyl]Ethoxy]- ,Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for pharmaceutical R&D use. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.