Description

2-(2-(2-(4-(Dibenzo[B,F][1,4]Thiazepin-11-Yl)Piperazin-1-Yl)Ethoxy)Ethoxy)Ethanol Dihydrochloride is a high-purity, pharmaceutically relevant organic salt with the CAS number 329216-69-5. This compound is a key advanced intermediate or active pharmaceutical ingredient (API) in the research and development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers. Its precise chemical structure makes it valuable for synthesizing compounds targeting specific biological pathways.

Application

• Pharmaceutical Research & Development (R&D): Serves as a critical building block or reference standard in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and psychiatric disorder research.
• Active Pharmaceutical Ingredient (API) Intermediate: Used in the scaled-up production of active drug substances under current Good Manufacturing Practice (cGMP) conditions.
• Biochemical & Pharmacological Studies: Employed as a tool compound in in vitro and in vivo studies to investigate receptor binding affinity, efficacy, and metabolic pathways.
• Reference Standard for Quality Control: Provides a high-purity benchmark for analytical method development, validation, and impurity profiling in pharmaceutical quality control laboratories.
• Academic & Institutional Research: Supports chemical and medicinal chemistry research in universities and government institutions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and clinical trial material production.

Basic Information

Product Name	2-(2-(2-(4-(Dibenzo[B,F][1,4]Thiazepin-11-Yl)Piperazin-1-Yl)Ethoxy)Ethoxy)Ethanol Dihydrochloride
CAS No.	329216-69-5
Molecular Formula	C25H34Cl2N4O3S
Molecular Weight	541.53 g/mol
Synonyms	11-[4-[2-[2-(2-Hydroxyethoxy)ethoxy]ethyl]piperazin-1-yl]dibenzo[b,f][1,4]thiazepine dihydrochloride; Quetiapine Impurity; Quetiapine Related Compound; Quetiapine Dihydrochloride Derivative; Dibenzo[b,f][1,4]thiazepine-11-(1-piperazinyl) derivative; 2-{2-[2-(4-{Dibenzo[b,f][1,4]thiazepin-11-yl}piperazin-1-yl)ethoxy]ethoxy}ethanol dihydrochloride
EINECS	Contact for details

Quality Control

Our 2-(2-(2-(4-(Dibenzo[B,F][1,4]Thiazepin-11-Yl)Piperazin-1-Yl)Ethoxy)Ethoxy)Ethanol Dihydrochloride is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, which includes batch-specific data and confirms compliance with agreed specifications. For advanced applications, we can supply material produced under current Good Manufacturing Practice (cGMP) guidelines upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.