Description

Quetiapine Sulfone is a key pharmaceutical intermediate and metabolite of the antipsychotic drug Quetiapine. Its precise synthesis and high purity are critical for research, development, and quality control processes within the pharmaceutical industry. This compound is primarily utilized by manufacturers and research institutions focused on neuropharmacology, drug metabolism studies, and analytical method development.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis and research of Quetiapine and related compounds.
• Reference Standard: Used as a certified reference material (CRM) for analytical method development and validation in quality control laboratories.
• Metabolite Studies: Essential for pharmacokinetic and pharmacodynamic research to understand the drug's metabolism and activity.
• Impurity Profiling: Serves as a known impurity standard to monitor and control the quality of active pharmaceutical ingredients (APIs).
• Biomedical Research: Employed in preclinical and clinical studies to investigate drug mechanisms and metabolic pathways.

Basic Information

Product Name	Quetiapine Sulfone
CAS No.	329216-65-1
Molecular Formula	C21H25N3O2S
Molecular Weight	383.51 g/mol
Synonyms	2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol S,S-dioxide; Quetiapine S,S-Dioxide; Quetiapine Sulfoxide (common misnomer); N-desalkyl Quetiapine Sulfone; ICI 204,636 Sulfone; 11-(4-{2-[2-(Hydroxyethoxy)ethyl]piperazin-1-yl}dibenzo[b,f][1,4]thiazepin) S,S-dioxide
EINECS	Contact for details

Quality Control

Our Quetiapine Sulfone is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR, MS). A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or manufacturing specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.